James McNulty Selected Research

7-deoxypancratistatin

6/2012

A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen.

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James McNulty Research Topics

Disease

16	Neoplasms (Cancer) 07/2018 - 03/2004
4	Infections 11/2018 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2019 - 03/2008
2	Colorectal Neoplasms (Colorectal Cancer) 06/2012 - 01/2011
2	Leukemia 03/2010 - 05/2009
1	Herpes Simplex Encephalitis (Herpes Encephalitis) 11/2018
1	Central Nervous System Infections (Central Nervous System Infection) 11/2018
1	Chronic Disease (Chronic Diseases) 12/2011
1	Prostatic Neoplasms (Prostate Cancer) 06/2011
1	Melanoma (Melanoma, Malignant) 02/2011
1	Adenocarcinoma 01/2011
1	Disease Progression 03/2010
1	Lymphoma (Lymphomas) 07/2005
1	Lymphoid Leukemia 03/2004

Drug/Important Bio-Agent (IBA)

12	pancratistatinIBA 07/2018 - 01/2005
5	AlkaloidsIBA 11/2018 - 05/2009
4	Acyclovir (Aciclovir)FDA LinkGeneric 11/2018 - 01/2016
3	Pharmaceutical PreparationsIBA 11/2018 - 02/2011
3	Tamoxifen FDA LinkGeneric 06/2012 - 03/2008
2	Estrogen ReceptorsIBA 01/2019 - 03/2008
2	Biological ProductsIBA 01/2019 - 12/2005
2	lycoraneIBA 11/2018 - 05/2009
2	Antiviral Agents (Antivirals)IBA 11/2018 - 01/2017
2	fosbretabulin (combretastatin A4)IBA 01/2017 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2011 - 03/2008
2	DNA (Deoxyribonucleic Acid)IBA 01/2011 - 07/2005
2	Paclitaxel (Taxol)FDA LinkGeneric 07/2005 - 01/2005
1	Letrozole (Femara)FDA LinkGeneric 01/2019
1	Anastrozole (Arimidex)FDA LinkGeneric 01/2019
1	exemestane (Aromasin)FDA Link 01/2019
1	Hormones (Hormone)IBA 01/2019
1	Aromatase InhibitorsIBA 01/2019
1	trans-dihydrolycoricidineIBA 11/2018
1	diphenyl (biphenyl)IBA 01/2017
1	StilbenesIBA 01/2017
1	JCTH-4IBA 06/2012
1	7-deoxypancratistatinIBA 06/2012
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2011
1	AndrogensIBA 06/2011
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2011
1	Growth InhibitorsIBA 01/2011
1	dihydronarciclasineIBA 01/2011
1	Mitochondrial DNA (mtDNA)IBA 01/2011
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2011
1	lycorineIBA 05/2009
1	Adenosine Triphosphate (ATP)IBA 03/2008
1	Amaryllidaceae AlkaloidsIBA 06/2007
1	Protein SIBA 06/2007
1	phenanthridoneIBA 06/2007
1	ElementsIBA 06/2007
1	PhosphatidylserinesIBA 07/2005
1	Etoposide (VP 16)FDA LinkGeneric 07/2005
1	Caspase 3 (Caspase-3)IBA 07/2005
1	aaptamineIBA 03/2004
1	isoaaptamineIBA 03/2004
1	demethyloxyaaptamineIBA 03/2004

Therapy/Procedure

3	Therapeutics 01/2019 - 07/2005
1	Drug Therapy (Chemotherapy) 02/2011
1	Radiotherapy 01/2005